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Return to the Home Page Learn the facts about folic acid enter a contest & meet our latest contest winners! Learn how you can get your free vitamins Go to the Press Room Additional resources and links Arriba Acido Folico en Espanol ï‹eºÑIëxu(N-eá

Why Go Folic?

The U.S. Preventive Services Task Force recommends that all women who could become pregnant get between 400-800 micrograms of folic acid daily.

Studies show that if all women consumed the recommended amount of folic acid before and during early pregnancy, up to 70 percent of all neural tube defects could be prevented. Recent studies indicate that folic acid supplementation may have added benefits for women's health.

GO FOLIC! promotes the concept of healthy nutrition and the benefits of daily supplementation of folic acid while enhancing the general health and well-being of clients.

Folic Acid Benefits Babies & Reduces Health Care Costs

Folic acid taken before conception reduces infant morbidity and mortality associated with folic acid deficiency. Folic acid supplementation:

  • Reduces by 70% the risk of neural tube defects (1 in 1000 U.S. births at an annual cost of approximately $294,000 per child)
  • May reduce the risk for low birth weight/premature babies (1 in 8 U.S. births at an average cost of $49,000 during the first year of life)
  • May reduce the risk of other birth defects, such as cleft lip and palate and defects of the cardiovascular system and urinary tract

Folic isn't just for women who are thinking about getting pregnant...

• In the U.S., 50% of all pregnancies are unplanned. Even though NTDs occur before most women know that they are pregnant, a 2007 March of Dimes/Gallop pole found that only 40% of women between the ages of 18-45 take a daily multivitamin.

    Molecular structure of folic acid
  • Folic acid plays an important role in the production of red blood cells. Individuals who are deficient in folic acid sometimes develop a form of anemia called megaloblastic anemia (characterized by a reduced number of red blood cells).
  • High levels of the amino acid homocysteine are independently associated with an increased risk of heart disease and stroke. It has been shown that taking folic acid lowers homocysteine levels in both men and women, but it is not yet known whether folic acid supplementation also lowers the risk of heart disease and stroke.
  • While further research is needed, studies have found that supplementation may also reduce the risk of colon, cervical and other cancers.

Medical conditions that increase the need for folic acid include:

• pregnancy and lactation
• alcohol abuse
• malabsorption
• kidney dialysis
• liver disease
• certain anemias

Clinic-Based Folic Acid Supplementation Works!

A 2006 project of the Michigan Department of Community Health targeting non-pregnant women found multi-vitamin usage increased from 35% to 82% following receipt of free vitamins. Other projects have seen similar results.

A systematic review of folic acid supplementation programs (Stockley & Lund, 2008) concluded that, "Health-care based initiatives can be effective and are more likely to be successful if they include making supplements easily available... and include elements that specifically target vulnerable women."

Doctor and patient talkingStarting the Conversation

Starting the conversation can be as simple as a handout and two questions. 1) Do you take a daily multi-vitamin? 2) Why or why not?

Resources for Health Care Staff

Clinic Forms

To order copies, email Shivaun.Nestor@sfdph.org


Why supplements instead of diet? A word about bioavailability...

The body absorbs folic acid more readily than it does food folate. Estimated absorption rates for folate and folic acid are:

  • 50% of the folate in food
  • 85% of the folic acid in "enriched" or "fortified" flour and grain products
  • 100% of the folic acid in a multi-vitamin

Medications that interfere with folic acid utilization include:

  • anti-convulsant medications
  • metformin
  • sulfasalazine
  • triamterene
  • methotrexate
  • barbiturates

A word about toxicity...

Intake of supplemental folic acid should not exceed 1,000 micrograms (µg) per day to prevent folic acid from triggering symptoms of vitamin B12 deficiency. Folic acid supplements can correct the anemia associated with vitamin B12 deficiency but will not correct changes in the nervous system that result from vitamin B12 deficiency. While there is now a simple, definitive lab test to detect, vitaimin B12 deficienl, Permanent nerve damage can occur if vitamin B12 deficiency is not treated.


Click here to download a copyof the references for this page. Click here to visit the Florida Folic Acid Coalition for further information geared towards health professionals.

Return to the Home Page Learn the facts about folic acid enter a contest & meet our latest contest winners! Learn how you can get your free vitamins Go to the Press Room Additional resources and links Arriba Acido Folico en Espanol ï‹eºÑIëxu(N-eá